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The precise mapping of these residues allows scientists to target the protein more effectively. Because TMPRSS2 is a host cell protease that the COVID-19 virus uses to enter human cells, it is an attractive target for .
The human TMPRSS2 (Transmembrane Protease, Serine 2) is composed of three distinct extracellular domains: SRCR Domain (Residues 150–242) Serine Protease (SP) Domain (Residues 243–492) 112149
Efficient production of fully active, SARS-CoV-2-priming ... - PMC The precise mapping of these residues allows scientists