The sequence represented by 22924 is part of a DNA probe used to investigate the binding behavior of (Peroxisome Proliferator-Activated Receptor alpha) and RXR (Retinoid X Receptor alpha).
: The binding is sensitive to the surrounding genetic architecture. Deleting specific flanking sequences (9-bp from the 5' end and 7-bp from the 3' end) reduces the formation to only a single complex. Scientific Context: PPAR and RXR 22924.rar
According to a study on Cooperative Formation of Higher Order Peroxisome Proliferator-activated Receptor Complexes, this sequence is a critical component for understanding how the rat heart-type peroxisome proliferator response element (HD PPRE) functions at a molecular level. Molecular Role and Interaction The sequence represented by 22924 is part of
If you are looking for a of the 36-bp sequence or its application in CRISPR or other genetic tools, let me know! I can also help you find the full experimental protocol associated with this specific probe. Scientific Context: PPAR and RXR According to a
: These complexes are observed when the sequence is incubated with nuclear extracts from specific cell lines, such as H4IIEC3 cells .