: Isolation of mesenteric arteries and thoracic aorta; use of Danish Myo tension systems to measure vessel contraction/relaxation.
: Western immunoblotting to detect the redox state of PKG and phosphorylation levels. 4. Results 23484.rar
: Discuss the potential for developing a new class of antihypertensives that specifically target the oxidative state of the cardiovascular system. : Isolation of mesenteric arteries and thoracic aorta;
: Use of C57BL/6 mice and specialized Cys42Ser KI (knock-in) mice that are resistant to PKG oxidative activation. 23484.rar