One of Yamazaki’s most notable technical contributions to the scientific community is her work on profiling the transcriptomics of the blood-brain barrier.

: She contributed to vital studies in Nature Neuroscience evaluating how liver-expressed (peripheral) apoE4 compromises synaptic plasticity and exacerbates brain amyloid pathology. ⚗️ Focus 2: Akari Yamazaki in Organic Chemistry

A significant portion of her co-authored work focuses on the apolipoprotein E (APOE) gene—specifically the ε4 allele, which is the strongest genetic risk factor for Alzheimer's disease.

In the physical sciences, Akari Yamazaki is a talented chemist at Shinshu University in Japan, working heavily within the Graduate School of Science and Technology. Her work leans toward the synthesis, reactivity, and properties of non-benzenoid aromatic compounds. Exploring Azulene Derivatives

Yamazaki's chemical research frequently focuses on and related fused-ring systems. Azulene is known for its deep blue color and unusual dipole moment, making its derivatives highly sought after for advanced materials and pharmaceuticals.