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Dendritic spines are tiny protrusions on neurons that receive input from other cells. Their size is a direct physical indicator of —larger spines generally correlate with stronger connections. This report examines how these structures change size (structural plasticity), which is a fundamental process underlying learning and memory. 2. Key Findings

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Download links * Insight. * Structural Biology and Molecular Biophysics. * CaMKII. * actinin. * long-term potentiation. * synapse. Dendritic spines are tiny protrusions on neurons that

The study investigates the role of specific proteins, including CaMKII (Calmodulin-dependent protein kinase II) and actinin , in managing the structural integrity and growth of the dendritic spine. * Structural Biology and Molecular Biophysics

Supplemental information, including data sets and molecular models, is also available for download on the same page. Synapses: Changing the size of dendritic spines - eLife