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This guide outlines how to interpret Serum Protein Electrophoresis (SPEP) results, which separate blood proteins into specific fractions to help diagnose conditions like multiple myeloma, liver disease, or inflammation.
You can find and download detailed clinical guides from these authoritative medical platforms: This guide outlines how to interpret Serum Protein
: Liver disease, kidney loss (nephrotic syndrome), or malnutrition. Increased : Dehydration. Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation. Alpha-2 Haptoglobin, Alpha-2 macroglobulin Increased : Acute phase reaction or nephrotic syndrome. Beta Transferrin, Complement Increased : Iron deficiency or high cholesterol. Two peaks ( ) are visible in capillary tests. Gamma Immunoglobulins (Antibodies) Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation
: Download the interpretation guide from FMC Tourcoing for a concise overview of quantitative values. Two peaks ( ) are visible in capillary tests
: The JNMG guide on anomalies provides specific indicators for bone pain or unexplained renal failure.
: Suggests Multiple Myeloma or MGUS. Broad Increase : Chronic infection or autoimmune disease. Key Patterns to Look For
: Access the Cerba laboratory document for standard reference values and capillary electrophoresis details. The Five Main Protein Fractions