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: The model requires several input files, typically one per chromosome, containing segregating sites and information on "called" sites.

: Because MSMC needs to know which regions of the genome could actually be called (filtering for quality and coverage), users must provide a Mask-file to exclude unreliable data. Download MSMC Maps from Here (Click on this text)

: Use tools like R to plot the results and interpret population changes over time. 5. Conclusion : The model requires several input files, typically