Theagle.cely.1.var

These track the number of other enhancers (EWS) or genes (GWS) located in the "window" between the enhancer and gene of interest, accounting for potential interference or competition.

: Likely represents the first variable or a specific variant in a ranked list of potential regulatory interactions. theagle.Cely.1.var

: Likely refers to the EAGLE tool or its associated database, EnhancerAtlas . These track the number of other enhancers (EWS)

Measures how closely the activity of an enhancer aligns with the expression patterns of a target gene. Measures how closely the activity of an enhancer

: This often denotes cell-type specificity , a core feature of EAGLE which allows it to distinguish between interactions that only occur in certain tissues.

The most interesting aspect of variables in this system is their ; unlike older models that required dozens of inputs, EAGLE uses only six core features to predict interactions with high accuracy:

Based on the gene's FPKM score (from RNA-seq data), representing the transcriptional activity level in specific tissues.